* Indicates Required Field

*Course Date:  April 19, 2012 May 17, 2012 June 17, 2012 July 19, 2012 August 16, 2012 September 13, 2012 October 18, 2012 November 15, 2012 December 13, 2012

*Name:

*Title:

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*Primary Affiliation: County Health Department Community-Based Organization DOH Headquarters Other

   *Name of Organization:

*Primary Setting: Hepatitis Laboratory HIV STD Family Planning Immunization TB & Refugee Health Adult Health General Clinic Epi Primary Care Other

 * If "Other," please identify: 

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*City:    *State:  

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Under Florida law, e-mail addresses are public records. If you do not want your e-mail address released in response to a public records request, do not send electronic mail to this entity. Instead, contact this office by phone or in writing.

*Email:

Learning Objectives

• Provide a review of the serological tests for hepatitis A, B, and C markers
• Provide a review of interpretation of hepatitis A, B, and C test results
• Provide an understanding of the differences between acute and chronic viral hepatitis infection and the serological makers associated with each
• Provide an opportunity to apply knowledge of viral hepatitis through case study presentations and discussion           
  

Pretest

MULTIPLE CHOICE - Select the correct answer

1. What hepatitis A (HAV) test is positive when someone has received hepatitis A vaccine or has been infected with HAV more than 6 months prior to the date of test? 

*2. What hepatitis B (HBV) test is used to determine acute HBV infection?

*3. What blood test should be positive when someone responds to hepatitis B vaccine?

*4. A case definition for hepatitis generally includes all except which one of the following:

*5. What hepatitis B test can you use to distinguish between immunity due to HBV infection and immunity due to vaccination?

*6. What blood test should be done routinely on pregnant women during the 1st trimester?

*7. What are the available initial screening tests for hepatitis C (HCV) infection?

*8. Which is a confirmatory test for HCV infection?

*9. How long does immunity last after hepatitis A immunization?

*10. You have received the following laboratory report:

anti-HAV IgM – positive
anti-HAV total – positive
anti-HBc IgM - negative
anti-HBc total – positive
HBsAg – positive, twice, eight months apart
anti-HCV EIA – positive with s/co 3.0
ALT – 900 (ULN – 45)
AST – 800 (ULN – 55)
The correct interpretation of these laboratory results is?

*11. You receive a laboratory report with the following hepatitis B marker results:

anti-HBs - negative
HBsAg – negative
anti-HBc IgM – negative
anti-HBc total – positive
Which of the following are possible interpretations?

*12. You receive a laboratory report with the following hepatitis test results:

anti-HBs - negative
HBsAg – negative
anti-HBc total – positive
anti HCV EIA – positive, s/co 2.8

A RIBA was done on this specimen and was negative.
The negative RIBA result indicated the initial anti-HCV EIA test result was a false positive.

*13. Post vaccination testing should be done on all persons who receive hepatitis A vaccine.

*14. You have received the following laboratory report:

Anti-HAV IgM – negative
Anti-HBc IgM – positive
HBsAg – positive
EIA anti-HCV – positive

A correct interpretation of these laboratory results is chronic hepatitis B, possible HCV infection.

*15. The CDC only recommends hepatitis A vaccine for travelers, MSM, and illegal drug users.

*16. In a public health screening program, if there is a positive CIA anti-HCV result with a signal-to-cut-off ratio of 9.8, then a supplemental confirmatory assay is not needed.

*17. In immunocompetent individuals anti-HAV IgG may appear early in the course of infection, remaining detectable for the lifetime of the individual and confering lifelong protection against infection.

*18. You received the following laboratory report:

HBsAg – negative
Anti-HBc – negative
EIA anti-HCV positive and indeterminate by RIBA
S/co = 3.0
RIBA - indeterminant

Additional laboratory evaluation using polymerase chain reaction (PCR) on this specimen was positive. These results indicate that the client was hepatitis C negative.

*19. The diagnosis of acute hepatitis A infection is confirmed during the acute stage of infection by the presence of IgM antibodies to HAV.

*20. Hepatitis B vaccine is a recombinant vaccine containing HBsAg protein.

*21. HAV replicates in the liver, is excreted in bile, and is shed in the stool.